姓名：

宋秀玲

性别：

女

职称：

副教授、博士生导师

所在部门：

卫生检验教研室

最后学历：

研究生

最高学位：

博士

电话：

13504308540

Email：

songxiuling@jlu.edu.cn

所在学科专业：

环境卫生与劳动卫生学招生

研究方向：

1. 环境与健康 2. 卫生检测技术研究

讲授课程：

《卫生化学》、《化妆品理化检验》、《实验室安全与管理》、《水质理化检验》等

教育经历：

2010.09 – 2013.06，金沙2004路线js5，卫生毒理学，博士

2008.09 – 2010.06，金沙2004路线js5，环境卫生与劳动卫生学，硕士

2002.09 – 2008.07，金沙2004路线js5，医事法学，学士

工作经历：

2017.09 - 至今   金沙2004路线js5，金沙，副教授

2014.07-2017.08  金沙2004路线js5，金沙，讲师

2013.12 -2017.12 金沙2004路线js5，金沙，博士后

科研项目：

国家自然科学基金委, 面上项目, 主持

吉林省科技厅，科技创新平台项目，主持

吉林省科技厅，重点研发项目，主持（合作单位）

吉林省科技厅，自然科学基金项目 , 主持

吉林省教育厅, 科学技术研究项目, 主持

吉林省卫生健康委员会，青年科技骨干培养项目,主持

国家自然科学基金委, 青年基金项目, 主持

金沙2004路线js5,交叉学科项目,  主持

金沙2004路线js5,白求恩计划项目, 主持

学术论文：

1. Tiantian Tian , Huan Pang , Kai Ma , Tianxiang Liu , Jiali Li , Zhixuan Luo , Meng Li , Qiohong Hou , Huifang Hao , Jianfei Dong , Haiying Du , Xiaomei Liu , Zhiwei Sun , Chao Zhao* , Xiuling Song *, Minghua Jin* The role of DRP1 mediated mitophagy in HT22 cells apoptosis induced by silica nanoparticles. Ecotoxicology and Environmental Safety, 2024,272 :116050

2. Yulan Guo , Jinbin Zhao , Xueer Ma , Ming Cai , Yuyang Chi , Chunmeng Sun , Shitong Liu , Xiuling Song^*, Kun Xu^*. Phytochemical reduces toxicity of PM2.5: a review of research progress. Nutr Rev. 2023, 16:nuad077.

3. YueZhai^#, HaoyanYu^#, XingxingLiu, MengfanZhang, RongpengHan, CaihongYin, XingchiLiu, HuiLi, JuanLi^*, XiulingSong^*. Visual detection of Staphylococcus aureus based on immunomagnetic separation and polymerase spiral reaction. Food Control, 2023, 1147, 109621

4. Xingxing Liu, Xue Du, Yanzhi Huang, Bo pang, Mengfan Zhang, Yingwei Ma, Xiaomu Wang, Xiuling Song^*, Jinhua Li^*, Juan Li^*. Rapid detection of four pathogens in bloodstream infection by antimicrobial peptide capture combined with multiplex PCR and capillary electrophoresis.Microchemical Journal, 2023, 185, 108199

5. Caihong Yin, Zhanyun Song, Xianghui Wang, Hui Li, Yue Liu, Qiulin Wang, Xin Feng^*, Xiuling Song^*. Development and clinical application of a rapid, visually interpretable polymerase spiral reaction for tcdB gene of Clostridioides difficile in fecal cultures. FEMS Microbiology Letters, 2023, 17: 370, 1-8.

6. Cai Hong Yin , Zhan Yun Song , Xing Xing Liu, Xiao Mu Wang, Ying Wang, Cheng Cheng Gao , Xiu Ling Song^* , Xin Feng^*. Comparison of Microdroplet Digital PCR Assays with Real-time Fluorescence Quantitative PCR for Clostridioides difficile Detection. Biomed Environ Sci, 2023, 36(7): 653-657.

7. Caihong Yin, Bo Pang, Yanzhi Huang, Jinhua Li , Tingyu Meng, Mengfan Zhang, Liang Zhang, Yanli Gao^* , Xiuling Song^*. Multiplex polymerase spiral reaction for simultaneous detection of Salmonella typhimurium and Staphylococcus aureus. Analytical Biochemistry, 2023, 667, 115086. 

8. Xiayu Zhang , Huifang Hao , Kai Ma , Huan Pang , Xinyue Li , Tiantian Tian , Shanshan Hou , Xiaofan Ning , Hao Wu , Qiaohong Hou , Meng Li , Yunxiang Sun , Xiuling Song^* , Minghua Jin^*. The role and mechanism of unfolded protein response signaling pathway in methylmercury-induced apoptosis of mouse spermatocytes germ cell-2 cells. Environmental Toxicology, 2023, 38(2):472-482. 

9. Shiyu He^#, Yanzhi Huang^#, Yingwei Ma, Haoyan Yu, Bo Pang, Xingxing Liu, Caihong Yin, Xiaomu Wang, Yuan Wei, Yuling Tian, Chao Zhao, Kun Xu, Juan Wang, Chunping Lv, Xiuling Song^*, Minghua Jin^*. Detection of four foodborne pathogens based on magnetic separation multiplex PCR and capillary electrophoresis. Biotechnology Journal, Biotechnol J. , 2022, 17(1):e2100335.

10. Yue Zhai^#, Xiangjun Meng^#, Li Li, Yushen Liu, Kun Xu, Chao Zhao, Juan Wang, Xiuling Song^*, Juan Li^*, Minghua Jin^*. Rapid detection of Vibrio parahaemolyticus using magnetic nanobead-based immunoseparation and quantum dot-based immunofluorescence. RSC Adv., 2021, 11, 38638-38647

11. Shiyu He, Hongbo Jang, Chao Zhao, Kun Xu, Juan Wang, Bo Pang, Xiaoxue Si, Minghua Jin, Xiuling Song^*, Juan Li^*. Rapid visualized isothermal nucleic acid testing of Vibrio parahaemolyticus by polymerase spiral reaction. Analytical and Bioanalytical Chemistry, 2020, 412(1): 93-101.

12. Shiyu He , Yanzhi Huang , Yanling Zhao , Bo pang, Lixue Wang, LiweiSun,  Haoyan Yu, Juan wang, Juan Li^*, Xiuling Song^*, Hui Li. A reverse transcription-polymerase spiral reaction (RT-PSR)-based rapid Coxsackievirus A16 detection method and its application in the clinical diagnosis of Hand, foot, and mouth disease[J].  Frontiers in Microbiology, 2020,11:734

13. Yue Zhai^#, Chao Zhao^#, Li Li, Kun Xu , Juan Wang, Xiuling Song^* , Hui Li^*. Production of Phage Display-Derived Peptide and the Application for Detecting Vibrio parahaemolyticus by Combined PCR Technology[J]. Food Analytical Methods , 2020,13, 1906–1917.

14. Li Li^#, Huiwen Zhang^#, Dandan Song, Kun Xu, Yan Zheng, Yushen Liu, Juan Li^*,  Xiuling Song^*. Simultaneous Detection of Three Zoonotic Pathogens Based on Phage Display Peptide and Multicolor Quantum Dots[J]. Analytical Biochemistry , 2020 ,608：113854.

15. Xiaoxue Si^# , Xiuling Song^# , Kun Xu, Chao Zhao, Juan Wang, Yushen Liu, Shiyu He, Minghua Jin,Hui Li*. Bovine serum albumin-templated MnO₂ nanoparticles are peroxidase mimics for glucose determination by luminol chemiluminescence. Microchemical Journal, 2019,149 :104050.

16. Bo Pang^#, Chao Zhao^#, Li Li, Xiuling Song^*, Kun Xu, Juan Wang, Yushen Liu, Kaiyue Fu, Hao Bao, Dandan Song, Xiangjun Meng, Xiaofeng Qu, Zhuping Zhang, Juan Li^*, Development of a low-cost paper-based ELISA method for rapid Escherichia coli O157:H7, Analytical Biochemistry, 2018, 542:58-62

17. Li Li, Dehui Yin, Kun Xu, Yushen Liu, Dandan Song, Juan Wang, Chao Zhao, Xiuling Song^*, Juan Li^*, A sandwich immunoassay for brucellosis diagnosis based on immune magnetic beads and Quantum dots, Journal of pharmaceutical and biomedical analysis , 2017, 141:79-86

18. Dandan Song^#, Xiaofeng Qu^#, Yushen Liu, Li Li , Dehui Yin, Juan Li, Kun Xu, Renguo Xie, Yue Zhai, Huiwen Zhang, Hao Bao, Chao Zhao, Juan Wang, Xiuling Song*, Wenzhi Song*, A Rapid Detection Method of Brucella with Quantum Dots and Magnetic Beads Conjugated with Different Polyclonal Antibodies, Nanoscale Research Letters, 2017, 12:179

19. Wen Ju^#, Xiuling Song^#, Gang Yan^#, Kun Xu, Juan Wang, Dehui Yin, Li Li, Xiaofeng Qu, Yangguang Li*, Juan Li*, Layer-by-Layer Assembly of Polyoxometalate-Pyrene-Decorated Fluorescent Microspheres for Suspension Immunoassay of Listeria Monocytogenes, Journal of Material Chemistry B, 2016, 4: 4287-4294

20. Xiuling Song^# , Bo Li^#, Kun Xu, Juan Liu, Wen Ju, Juan Wang, Xiao-dong Liu, Juan Li* , Yan-fei Qi*, Cytotoxicity of water-soluble mPEG-SH-coated silver nanoparticles in HL-7702 cells, Cell Biology and Toxicology, 2012, 28(4): 225-237

21. 宋秀玲, 翟玥, 李娟, 徐坤, 李丽, 陈锋, 韩雪飞, 赵超, 王娟, 刘玉申,张惠雯 ,袁博超, 史雪宁, 曲世芳. 副溶血性弧菌特异性结合的多肽V1及其用途[P]. 吉林：CN113388613B, 2022. (授权)

22. 宋秀玲, 翟玥, 李娟, 徐坤, 李丽, 陈锋, 韩雪飞, 赵超, 王娟, 刘玉申,张惠雯 ,袁博超, 史雪宁, 曲世芳. 副溶血性弧菌特异性结合的多肽V2及其用途[P]. 吉林：CN113403304B,2022. (授权)

23. 宋秀玲,唐小飞,司晓雪,李娟,徐坤,赵超,王娟,王琼,胡雯,邓璐,张加美. 可视化基于免疫磁珠检测金黄色葡萄球菌试剂盒[P]. 吉林省：CN112649602A, 2020.

24. 宋秀玲, 孟祥君, 李娟, 徐坤, 李丽, 刘玉申, 翟玥, 宋丹丹, 王娟, 赵超. 基于磁性分离和量子点标记的副溶血性弧菌检测试剂盒[P]. 吉林省：CN107045061B,2019.(授权)

25. 宋秀玲, 司晓雪, 唐小飞, 赵超, 王娟, 徐坤, 李卉, 刘玉申, 张惠雯, 何施羽,金明华. 一种葡萄糖的检测方法[P]. 吉林省：CN110231486A,2019.

26. 宋秀玲, 翟玥, 李娟, 徐坤, 李丽, 陈锋, 韩雪飞, 赵超, 王娟, 刘玉申,张惠雯 ,袁博超, 史雪宁, 曲世芳. 副溶血性弧菌特异性结合的多肽及其用途[P]. 吉林：CN108753769A,2018. (授权)

著作教材：

1.《现代卫生化学》第3版，人民卫生出版社，2021，编委

2.《现代妇产科及新生儿院内感染诊疗与护理》，吉林科学技术出版社，2018，

副主编

2.《卫生化学习题集》第3版，人民卫生出版社，2017，编委

3.《儿科感染性疾病临床手册》，人民卫生出版社，2016，编委

获奖情况：

科研获奖：

1.多酸化合物抗病毒的作用研究，吉林省科学技术奖二等奖，2016，第五名

2.多糖抗辐射和抗肿瘤作用及其机制研究，吉林省预防医学会，吉林省公共卫生科学技术奖，二等奖，2015 ，第一名

3.多酸化合物抗流感病毒、乙型肝炎病毒的作用研究，吉林省公共卫生科学技术奖，一等奖，2014 ，第七名

教学获奖：

1. 金沙2004路线js5第八届青年教师比赛二等奖，2016

2. 金沙2004路线js5青年教师岗前培训优秀教案二等奖，2014

社会兼职：

中华预防医学会卫生检验分会委员、中华预防医学会农村饮水与环境卫生专委会委员、中国老年保健医学研究会老年营养健康分会委员、吉林省预防医学会卫生检验专业常务委员、《环境卫生学杂志》青年编委